ABOUT THE LAB
The goal of LaBIS research is to understand systemic molecular and biochemical interactions in organisms of economic interest, focusing from fermentation promoted by fungi and bacteria to produce bioproducts to the digestion of insects that impact agriculture. The projects seek to integrate different sources of information using classical approaches of computational biology and bioinformatics plus methodologies for the analysis of large volumes of data in Molecular Biology.
PRINCIPAL RESEARCHER
Marcelo Mendes Brandão
Coordination
LINES OF RESEARCH
🧑🔬 New tools for analysis of molecular and biological data
🧑🔬 Systems Biology Applied to Agriculture
🧑🔬 Systemic and integrative characterization of Saccharomyces cerevisiae transcriptomics for the production of bioproducts
ACCREDITED GRADUATE PROGRAM
- Programa de Pós-Graduação em Genética e Biologia Molecular da Universidade Estadual de Campinas (UNICAMP)
TEAM
Dr. Marcelo Mendes Brandão
Researcher
brandaom@unicamp.br
(19) 3521.1118
SERVICES
- Experiments for the analysis of transient gene expression;
- Construction of cDNA libraries and genomic libraries;
- Analysis of R&D projects in the field of Genetic Engineering;
- Isolation and characterization of genes; Cloud computing services and High Performance Computing;
- Analysis of R&D projects in the area of Bioinformatics and omics;
- RNA library construction
PUBLICATIONS
Ciamponi, F.E., Procópio, D.P., Murad, N.F., Franco, T.T., Basso, T.O., Brandão, M.M. Multi-omics network model reveals key genes associated with p-coumaric acid stress response in an industrial yeast strain. (2022) Scientific Reports, 12 (1), art. no. 22466. DOI: 10.1038/s41598-022-26843-2. OPEN ACCESS: All Open Access, Gold, Green
Béliveau, C., Gagné, P., Picq, S., Vernygora, O., Keeling, C.I., Pinkney, K., Doucet, D., Wen, F., Johnston, J.S., Maaroufi, H., Boyle, B., Laroche, J., Dewar, K., Juretic, N., Blackburn, G., Nisole, A., Brunet, B., Brandão, M., Lumley, L., Duan, J., Quan, G., Lucarotti, C.J., Roe, A.D., Sperling, F.A.H., Levesque, R.C., Cusson, M. The Spruce Budworm Genome: Reconstructing the Evolutionary History of Antifreeze Proteins. (2022) Genome Biology and Evolution, 14 (6), art. no. evac087. DOI: 10.1093/gbe/evac087. OPEN ACCESS: All Open Access, Gold, Green
Murad, N.F., Silva-Brandão, K.L., Brandão, M.M. Mechanisms behind polyphagia in a pest insect: Responses of Spodoptera frugiperda (J.E. Smith) strains to preferential and alternative larval host plants assessed with gene regulatory networks. (2021) Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 1864 (3), art. no. 194687. DOI: 10.1016/j.bbagrm.2021.194687.
Murad, N.F., Brandão, M.M. Probabilistic Graphical Models Applied to Biological Networks. (2021) Advances in Experimental Medicine and Biology, 1346, pp. 119-130. DOI: 10.1007/978-3-030-80352-0_7.
de Barros Dantas, L.L., Brandão, M.M. Interactomes: Experimental and In Silico Approaches. (2021) Advances in Experimental Medicine and Biology, 1346, pp. 107-117. DOI: 10.1007/978-3-030-80352-0_6.
Silva-Brandão, K.L., Murad, N.F., Peruchi, A., Martins, C.H.Z., Omoto, C., Figueira, A., Brandão, M.M., Trigo, J.R. Transcriptome differential co-expression reveals distinct molecular response of fall-armyworm strains to DIMBOA. (2021) Pest Management Science, 77 (1), pp. 518-526. DOI: 10.1002/ps.6051
Brandão, M.M., Dantas, L.L., Silva-Filho, M.C. AtPIN: Arabidopsis thaliana protein interaction network. (2009) BMC Bioinformatics, 10, art. no. 454. DOI: 10.1186/1471-2105-10-454. OPEN ACCESS: All Open Access, Gold, Green
CONTACT
Marcelo Mendes Brandão
Researcher
Email: mbrandao@unicamp.br
Group Photos
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